Glutathione in liver diseases and hepatotoxicity. Semantic Scholar Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury Shang 2016 Oxidative Medicine and Cellular Longevity Wiley Online Library Principal cysteine pathways in cellular metabolism. The liver removes Download Scientific Diagram Cells need a steady supply of antioxidants to defend themselves, and glutathione is the body's master defender. Yet, daily stress and ageing can deplete glutathione faster than we can make it. NAC + Glutathione Metabolism and Its Implications for Health ScienceDirect